Lupron

[Admin]

Lupron Depot® (leuprolide acetate for depot suspension) is used for the management of endometriosis, including pain relief and reduction of endometriotic lesions. The most common side effects with Lupron Depot are generally those related to low estrogen levels, including hot flashes, headaches and vaginal dryness. A small amount of bone loss (average 3.2% at month six) may also occur during therapy with Lupron Depot alone, but usually is partially or completely recovered after you stop taking Lupron Depot.

Women taking Lupron Depot plus norethindrone acetate 5 mg daily may experience hot flashes, headache, nausea/vomiting, depression/changes in mood, and weakness. Lupron Depot given with norethindrone acetate may lower your HDL-cholesterol level (the "good" cholesterol). Whether this change increases your long-term risk of heart disease is not known. Norethindrone acetate should be used with caution in women with cardiovascular risk factors including lipid abnormalities and cigarette smoking. Please refer to the norethindrone acetate prescribing information for warnings, precautions, contraindications, and adverse events.